303.526.7402 For 30 years, we’ve helped clients move ideas from the napkin into production. Let’s talk about your brilliant medical device ideas. We’re here to make you successful, so the IP stays with you, not us. Evergreen’s areas of expertise include: — product development — contract manufacturing — regulatory compliance Learn more at EvergreenResearch.com/Be1 Be Brilliant. Of course, there remains much more to be done. Based on decades of experience in the public sphere, Valuck also sees a key role for the private sector in the crisis. “After seeing all the things that have been done well so far, academia, policy, and money still can’t fix every problem or solve every need,” he says. “There are still issues that doctors, patients, and law enforcement struggle with on the ground.” That gap spurred Valuck to found the digital health company OpiSafe™ (Denver, Colorado), which has produced a suite of apps aimed at helping doctors prescribe according to best practices, monitor patterns of use in individual patients, and notice red flags for early detection and intervention. “Opioid use disorder shows up as a complex con- stellation of behaviors and signals,” says Valuck. “Doctors can identify the pattern if they can see it. OpiSafe shows them all the data points.” OpiSafe also offers an app for law enforcement and the lay public, OpiRescue™, to help guide untrained bystanders in how to manage a poten- tialoverdosevictimwhilewaitingformedicalfirst responders to arrive. It’s likely that software and machine learning will play an increasing role in curbing opioid 23 2019-2020 / / BIOSCIENCECOLORADO