C = CBSA MEMBER Hiberna Corporation Boulder Pursuing the potential clinical application of hibernation in order to slow metabolism, thereby extending survival limits in traumas that reduce oxygen to certain cells, e.g. in the heart and brain. C Horizon Therapeutics Illinois www.horizontherapeutics.com Horizon Therapeutics plc is a biopharmaceutical company focused on improving patients’ lives by identifying, developing, acquiring and commercializing differentiated and accessible medicines that address unmet medical needs. We market 11 medicines through our rare disease, rheumatology and primary care business units. Hospira - a Pfizer company Boulder www.hospira.com Supplies injectably generic and specialty pharmaceuticals. The Colorado site specializes in the supply of active pharmaceutical ingredients for both internal and external markets. C i2 Pharmaceuticals, Inc. Boulder www.i2pharma.com Creates tools for pharmaceutical drug discovery and development, in addition to proprietary medicinal chemistry services for the expansion of intellectual property protection of early- late-stage pharmaceutical assets. C IASO Biomedical, Inc. Centennial www.iasobiomedusa.com Developing a drug as an alternative to currently-available testosterone replacement therapy by stimulating the body’s own production of testosterone. ICVrx, LLC Denver Creating a new treatment category for epilepsy by reformulating drugs for brain delivery administered through implantable pumps. Site-specific computerized drug delivery is promising for improving epilepsy therapy in a significant proportion of refractory patients. C IM Therapeutics Broomfield www.imtherapeutics.com ImmunoMolecular Therapeutics is a private clinical stage biotech company developing a therapeutic approach for the treatment of Type I Diabetes. C Immunoah Therapeutics Aurora www.immunoah.com Focuses on researching and developing proprietary antibodies in the field of cancer immunotherapy. C Genentech California www.gene.com Using human genetic information to discover, develop, manufacture and commercialize medicines to treat patients with serious or life-threatening medical conditions. Genesis Laboratories, Inc. Wellington www.genesislabs.com Provides services to clients in the agrochemical and pharmaceutical industries, rodenticide research and development, as well as invasive species, zoonotic disease, and conservation research. GeneThera, Inc. Westminster www.genethera.net Develops and markets the latest molecular technologies to eradicate “cross over” diseases such as Johne’s Disease, Mad Cow Disease, Chronic Wasting Disease, and E.coli. Develops assay tests and vaccines to eradicate the threat to humans of diseases transmitted up the food chain by cattle, elk and deer. GenoFAB Boulder www.genofab.com Today, biotechnology products are engineered rather than discovered. R&D programs go through iterations of a data-driven product development cycle. We develop an ecosystem of software applications that help life- science organizations design, fabricate, and characterize synthetic DNA molecules. C GlaxoSmithKline United Kingdom www.gsk.com Produces medicines that treat six major disease areas – asthma, virus control, infections, mental health, diabetes and digestive conditions as well as vaccines and new treatments for cancer. C GlobeImmune, Inc. Louisville www.globeimmune.com GlobeImmune is developing Tarmogen product candidates to treat cancer and infectious diseases. Greffex, Inc. Aurora www.greffex.com Global leader in the delivery of accelerated pandemic and bio-terror vaccines using the world’s first universal platform, the GREVAX™ Vaccine Platform. HemoGenix Colorado Springs www.hemogenix.com Assay development laboratory specializing in developing predictive in vitro assay platforms for primary human and animal target cells and stem cell hemotoxicity testing. C HepQuant, LLC Aurora www.hepquant.com HepQuant-E is non-invasive, uses stable (not radioactive) isotopes, and relies on natural, well-defined hepatic functions to measure the portal circulation. C Editas Medicine Boulder, Massachusetts www.editasmedicine.com Editas Medicine is building the leading genome editing company dedicated to treating patients with genetically defined diseases. ELISA Tech Aurora www.elisatech.com Provides immunoassays for the measurement of cytokines, growth factors, and lipid inflammatory mediators. Entero Track Centennial www.enterotrack.com Next generation monitoring of gastrointestinal allergic diseases. C Evolve Biologics Ontario, Canada www.evolvebiologics.com Evolve is a new kind of biologics company founded for a clear purpose: bringing critical plasma proteins to the people who need them. C Flagship Biosciences, Inc. Westminster www.flagshipbio.com Flagship Biosciences Inc. delivers comprehensive tissue profiling for predictive diagnostics in drug therapy using an Artificial Intelligence (AI) enabled computational tissue analysis (cTA®) pathology analytics platform. Our intuitive data reporting gives researchers, clinicians, and drug developers the actionable information needed to drive better clinical results for patients. By delivering novel, useful tissue data in a timely manner, Flagship has become an indispensable partner to bio/pharma companies in their development of novel therapeutics. C FluoroFinder, LLC Broomfield www.fluorofinder.com Software as a Service (SaaS) experiment design tool for flow cytometry, that dramatically improves a medical researcher’s productivity and quality, while reducing costs. FluTrends International / STS Health Denver, Aurora www.stshealth.com Develops and commercializes products for the prevention of influenza. C Gates Biomanufacturing Facility Aurora www.gatesbiomanufacturing.com Helps clients accelerate the translation of their discoveries into human clinical trials as efficiently and cost effectively as possible. C GENASSIST, Inc. Greenwood Village www.genassistabcs.com A preconceptional, prenatal and pediatric service business that provides consulting services to patients referred by healthcare providers to help the patient interpret laboratory test results and develop a management plan. 47 2018-2019 / / BIOSCIENCECOLORADO